The Wolverines, the No. 8 seed in the bracket, begin tournament play against No. 9 seed Iowa on Thursday.
Katelynn Flaherty earned a spot on the All-Big Ten team, while Thome earned All-Freshman honors.
A date with Maryland, the Big Ten regular-season champion and No. 5 team in the country, awaits the unlucky winner on Friday.
Michigan was just 10-for-32 from the floor in the first half and was never able to recover from the 34-23 halftime deficit that its poor shooting created.
The Wolverines are fifth in the conference, have won five out of their last six games and have only one game left against Rutgers before the conference tournament.
After a rough start to the season, Thome has worked up to 65 percent from the charity stripe.
The Wolverines went into halftime with a five-point lead.
After a bumpy start to the conference schedule, the Wolverines have won four of their last five games.
The 2016 senior class was the first class Kim Barnes Arico coached at Michigan after beginning her tenure at Michigan four years ago.
Michigan and Penn State played even for most of the game, but the Wolverines pulled out a win.