With a two-handed alley-oop slam on No. 12 Purdue’s first possession, preseason All-Big Ten center JaJuan Johnson and the Boilermakers sent a message to the Michigan men’s basketball team — they weren’t going to be stopped.

Johnson finished with 22 points and eight rebounds, and despite a valiant effort from the Wolverines, Purdue (1-0 Big Ten, 12-1 overall) defeated Michigan 80-57 Tuesday afternoon at Crisler Arena.

Sophomore point guard Darius Morris — Michigan’s leading scorer and the reigning Big Ten Player of the Week — did not start due to an undisclosed violation of team rules. He was replaced by junior guard Stu Douglass. Morris entered the game at the first media timeout.

But Purdue took advantage of Morris’s initial absence, looking positively unbeatable in the opening minutes. The Boilermakers didn’t miss a shot until four and a half minutes had elapsed in the contest.

In Morris’s absence, the Wolverines (0-1 Big Ten, 10-3 overall) were hounded by Purdue’s intense man-to-man pressure and couldn’t get open shots on offense. They quickly found themselves down 19-3.

“At the start they got out to a run, and we had no one to calm us down, really,” sophomore guard Matt Vogrich said after the game. “(Morris) is a great ball handler. With their pressure defense, we needed him.”

Douglass scored Michigan’s next eight points and finished the half leading all players with 13 points.

Aided by Douglass’s hot shooting and two 3-pointers from freshman forward Evan Smotrycz, the Wolverines went on a 23-6 run to take their only lead of the game at 26-25.

But the Boilermakers knocked down a 3-pointer with under a minute to go in the half, and Michigan then squandered its opportunity to make the last shot. Purdue seized the momentum back, and the team carried it over to the second half — quickly opening a 10-point lead.

“We wanted to get the last shot of the half,” Michigan coach John Beilein said. “(The players) were pretty fired up today to play. That sometimes can be a negative. Basketball is a game of poise, and at the end of the first half, we needed to just control the tempo right until the very end.”

A layup from redshirt freshman forward Jordan Morgan cut the deficit to three points with 13:22 left in the game, but from there it was all Boilermakers.

Purdue went on a 22-7 run, carving up Michigan’s defense just like it did at the game’s start.

Johnson was a presence in the paint all game, and though he was just 6-for-16 from the field, his 10-for-10 performance from the free throw line made up for it. And when the Wolverines gave help on defense when Johnson had the ball in the post, it opened up opportunities for Purdue’s guards.

The other All-Big Ten Boilermaker — guard E’Twaun Moore — finished with 21 points, and guard Ryne Smith had 17 points, including a career-high five 3-pointers. Several of Purdue’s threes killed any momentum Michigan was trying to build. Beilein called them “daggers” after the game.

But it was the Boilermakers’ defense that caused the most trouble all afternoon. With many Wolverines seeing their first Big Ten action, Purdue represented a rude welcome with its intense, physical pressure both on the ball and off. Beilein said the game would serve as a “great teaching experience” for his young team.

“(Purdue) came in very strong, very physical, denying us many things that we like to do,” Beilein said. “We had to be able to counter. We’re not at that level where we really know to counter aggressively against a team like that.”

“We’ve gotten better at it, but not against a team like Purdue who’s very good at that,” Beilein said, adding that Purdue’s defense is “not a gimmick.”

Michigan shot just 38.2 percent from the field and turned the ball over 14 times, leading to 20 points for the Boilermakers.

As their frustration mounted, the inexperienced Wolverines saw the game rapidly slip away.

“Our guys just did a good job of clamping down on defense,” Johnson said. “Even when (Michigan) made their run, I could sense that we were the older team. We were a little bit more composed during certain situations … They’re a young team, and I feel like as the Big Ten season goes on, they’ll only get better.”